Clinical tests

Thanks to the collaboration with a network of clinics, specialized laboratories, research institutes and Contract Research Organizations (CRO), Alidans offers a wide range of services for clinical trials aimed at ensuring the safety, efficacy and regulatory compliance of products intended for the cosmetic, food, medical devices and chemical sectors.

Types of Clinical Studies

Phases I, II, III and Post-Marketing Studies (Phase IV)

Phase I: First evaluation of safety, tolerability and dosage in healthy volunteers or small groups of patients.
Phase II: Pilot studies to evaluate efficacy and determine the optimal dosage in patients with specific conditions.
Phase III: Large-scale multicenter studies to confirm safety and efficacy, necessary for regulatory approval.
Phase IV (Post-Marketing): Monitoring of long-term effects, safety and new indications for use post-marketing.
Randomized Controlled Trials (RCTs): Rigorous tests to evaluate the efficacy and safety of products.
Tolerability Studies: To evaluate adverse reactions and safety in specific populations (e.g. pediatric, elderly).

Clinical Evaluation Methodologies and Techniques

Clinical and Dermatological Evaluation: Measurement of sensitization, irritation and tolerability of topical products through tests conducted by specialists.
Instrumental and Biometric Methods: Use of advanced instruments (e.g. corneometer, cutometer, spectrophotometer) to analyze parameters such as hydration, elasticity and skin pigmentation.
Questionnaires and Self-Assessment of Volunteers: Collection of volunteers' perceptions through standardized questionnaires.
Monitoring of Clinical Biomarkers: Measurement of biological indicators (e.g. inflammatory markers, lipid profiles) to evaluate the effects of foods, supplements and medical devices.

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Application in key sectors

Cosmetics

Safety and Tolerability Assessment

Skin Patch Tests: Assessment of the tolerability and irritant potential of cosmetic products.
Phototoxicity and Photoirritation: Tests to assess the irritant potential of products exposed to sunlight.

Functional Efficacy Claims
Skin Hydration and Elasticity Studies: Measurements to support claims such as "intense hydration" or "improved elasticity".
Wrinkle Reduction and Anti-Aging Effects: Imaging studies to demonstrate smoothing and anti-aging effects.

Food Industry

Safety and Efficacy of Food Supplements

Gastrointestinal Tolerability: Clinical tests to assess tolerability and absence of significant adverse effect.
Nutrient Bioabsorption: Assessment of the absorption of nutrients and bioactive compounds.

Nutritional and Functional Claims

Antioxidant Activity: Monitoring of effects on oxidative stress indicators.
Metabolic Impact and General Well-Being: Studies on the effect of supplements on metabolism, weight management and general well-being.

Medical Devices Sector

Biocompatibility and Material Safety

Biocompatibility Clinical Studies: Evaluation of the tolerability of materials in contact with skin and mucous membranes.
Safety of Use in Therapeutic Contexts: Tests to confirm the compatibility of medical devices with human tissue.

Therapeutic Efficacy Claims

Wound Healing and Tissue Regeneration: Studies to verify the effectiveness of medical devices in the healing process.
Release of Active Substances: Monitoring the effectiveness of controlled release systems.

Specific Chemicals and Ingredients

Safety of Use Evaluation

Skin and Systemic Tolerability: Tests to ensure the safety of chemicals in contact with the skin or ingested.
Ocular Irritation and Sensitivity: Studies to evaluate the safety of substances with potential contact with the eyes.

Functional Claims and Toxicological Assessment

Functional Claims (e.g. Antimicrobial, Moisturizing): Testing to demonstrate the efficacy of chemical ingredients in specific formulations.
Monitoring of Toxicological Biomarkers: Testing to ensure that substances do not pose acute or chronic toxicological risks.

And other custom tests: our testing offering is constantly expanding to meet the dynamic needs of the industry. We are ready to develop new customized solutions to meet the specific requirements of our customers.

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